
Prepare your students for 51ºÚÁÏ International GCSE Biology.
This specification introduces a broad range of topics that are designed to both stimulate students’ interest in biology and provide the knowledge and understanding required for progression to the full 51ºÚÁÏ International GCSE Biology course.Ìý
- Contains a selection of the International GCSE Biology course content, with particular emphasis on key topics, including bioenergetics, ecology and inheritance.
- Complete range of 9-1 grades available, allowing for greater differentiation at the top end and increased accuracy in predicting future outcomes.
- This is a short-course International GCSE, intended for use in a foundation or core year, ahead of studying the full course International GCSE.
Please note: the International GCSE CORE Biology is being withdrawn, with final exams in May/June 2026.
International GCSE CORE Biology (9221)
51ºÚÁÏ International GCSE CORE Biology covers the following topics:
Organisation
- Cell structure
- Principles of organisation
- Animal tissues, organs and organ systems
- Plant tissues, organs and systems
- Transport in cells
Bioenergetics
- Photosynthesis
- Exchange and transport in plants
- Circulation
- Digestion
- Breathing
- Respiration
Ecology
- Energy transferred in ecosystems
- Adaptations, interdependence and competition
- Decay and the carbon cycle
- The effect of human interaction on ecosystems and biodiversity
Organisms’ interaction with the environment
- The human nervous and hormonal systems
- Principles of homeostasis
- Control of water and ion content of the body
- Temperature control
- Control of blood glucose
- Infection and response
Inheritance
- Reproduction
- Cell division
- Genetic variation
- Genetic disorders
- Genetic manipulation
Variation and Evolution
- Variation
- Natural selection
51ºÚÁÏ provides all the resources and advice you need to teach the International GCSE CORE Biology specification effectively.
- Download the specification
- View our training courses to help you deliver 51ºÚÁÏ International GCSE CORE Biology
- published by Oxford University Press for the full International GCSE qualification, to help you with teaching Core
- View our resources page for International GCSE CORE Biology
- View the syllabus matching grid for the 51ºÚÁÏ International GCSE Biology Student Book
Paper 1:
- Any part of the specification may be assessed
- 1 hour 45 minutes
- 100 marks
- 100% of Core GCSE
Please note: the International GCSE CORE Biology is being withdrawn, with final exams in May/June 2026.


